Placeholder image of a protein
Icon representing a puzzle

555: Symmetric Beta Core Design Puzzle 1

Closed since almost 14 years ago

Intermediate Overall Design Symmetry

Summary

Created
May 09, 2012
Expires
Max points
100
Description

The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 9,812
  2. Avatar for L'Alliance Francophone 2. L'Alliance Francophone 83 pts. 9,802
  3. Avatar for Void Crushers 3. Void Crushers 69 pts. 9,715
  4. Avatar for Contenders 4. Contenders 56 pts. 9,705
  5. Avatar for Go Science 5. Go Science 45 pts. 9,693
  6. Avatar for Deleted group 6. Deleted group pts. 9,659
  7. Avatar for foldeRNA 7. foldeRNA 29 pts. 9,654
  8. Avatar for SETI.Germany 8. SETI.Germany 23 pts. 9,538
  9. Avatar for Gargleblasters 9. Gargleblasters 18 pts. 9,529
  10. Avatar for FoldIt@Netherlands 10. FoldIt@Netherlands 14 pts. 9,490
  1. Avatar for Schleicher 51. Schleicher Lv 1 41 pts. 9,525
  2. Avatar for spdenne 52. spdenne Lv 1 40 pts. 9,525
  3. Avatar for Deleted player 53. Deleted player pts. 9,521
  4. Avatar for Steven Pletsch 54. Steven Pletsch Lv 1 38 pts. 9,517
  5. Avatar for randomlil 55. randomlil Lv 1 37 pts. 9,510
  6. Avatar for Jim Fraser 56. Jim Fraser Lv 1 37 pts. 9,507
  7. Avatar for sirenbrian2 57. sirenbrian2 Lv 1 36 pts. 9,497
  8. Avatar for benjy33 58. benjy33 Lv 1 35 pts. 9,494
  9. Avatar for cobaltteal 59. cobaltteal Lv 1 35 pts. 9,491
  10. Avatar for ViJay7019 60. ViJay7019 Lv 1 34 pts. 9,490

Comments

beta_helix Staff Lv 1

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.