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571: Tissue Regeneration Design Puzzle

Closed since almost 14 years ago

Beginner Overall Design

Summary

Created
June 07, 2012
Expires
Max points
100
Description

We are giving you a 10 residue helix positioned over a hydrophobic groove where binding occurs in nature. This native binding region in marked by unfrozen side chains. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle. Read the new blogpost for more details.

Top groups

  1. Avatar for Gargleblasters 11. Gargleblasters 13 pts. 9,508
  2. Avatar for Russian team 12. Russian team 10 pts. 9,504
  3. Avatar for Piratenpartei Deutschland 13. Piratenpartei Deutschland 7 pts. 9,501
  4. Avatar for 7Monkeys 14. 7Monkeys 6 pts. 9,490
  5. Avatar for SETI.Germany 15. SETI.Germany 4 pts. 9,490
  6. Avatar for Deleted group 16. Deleted group pts. 9,486
  7. Avatar for BOINC@Poland 17. BOINC@Poland 2 pts. 9,480
  8. Avatar for Freedom Folders 18. Freedom Folders 2 pts. 9,479
  9. Avatar for Team Canada 19. Team Canada 1 pt. 9,475
  10. Avatar for Aperture Science 20. Aperture Science 1 pt. 9,475
  1. Avatar for gcm24 61. gcm24 Lv 1 39 pts. 9,515
  2. Avatar for harp 62. harp Lv 1 38 pts. 9,515
  3. Avatar for multaq 63. multaq Lv 1 37 pts. 9,514
  4. Avatar for Deleted player 64. Deleted player pts. 9,513
  5. Avatar for keithv 65. keithv Lv 1 36 pts. 9,512
  6. Avatar for Datstandin 66. Datstandin Lv 1 35 pts. 9,511
  7. Avatar for AsDawnBreaks 67. AsDawnBreaks Lv 1 35 pts. 9,511
  8. Avatar for alwen 68. alwen Lv 1 34 pts. 9,511
  9. Avatar for Incongruous 69. Incongruous Lv 1 34 pts. 9,511
  10. Avatar for gramps 70. gramps Lv 1 33 pts. 9,510

Comments

mottiger Lv 1

puzzle is open on the design overview page but the status is unreleased.
are you working on it right now to bring it up?

BootsMcGraw Lv 1

I'm not sure if any of the other top scorers on this puzzle are seeing this, but I am finding that saturating this helix with aromatics is producing the highest scores.

I doubt highly that a real-life helix could contain so many tryptophans, tyrosines, and phenylalanines, yet remain a stable structure.

We've seen this scoring bug, before.