Placeholder image of a protein
Icon representing a puzzle

577: CASP10 Refinement Puzzle: TR688

Closed since almost 14 years ago

Intermediate Overall Prediction

Summary

Created
June 15, 2012
Expires
Max points
100
Description

This target was originally 196 residues, but has been trimmed down to 185. We have been told that almost 78% of this model matches the native, so we are giving you the 3 templates that were used to generate this model. Maybe by moving the alignment around using the Alignment Tool you'll be able to completely match the native. More info in the puzzle comments.

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 12,841
  2. Avatar for Go Science 2. Go Science 81 pts. 12,831
  3. Avatar for Void Crushers 3. Void Crushers 64 pts. 12,806
  4. Avatar for FoldIt@Netherlands 4. FoldIt@Netherlands 50 pts. 12,776
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 39 pts. 12,714
  6. Avatar for Anthropic Dreams 6. Anthropic Dreams 30 pts. 12,615
  7. Avatar for HMT heritage 7. HMT heritage 23 pts. 12,554
  8. Avatar for foldeRNA 8. foldeRNA 17 pts. 12,546
  9. Avatar for putting the eat in meat 9. putting the eat in meat 12 pts. 12,530
  10. Avatar for Gargleblasters 10. Gargleblasters 9 pts. 12,373
  1. Avatar for smilingone
    1. smilingone Lv 1
    100 pts. 12,831
  2. Avatar for Wildcat777 2. Wildcat777 Lv 1 99 pts. 12,803
  3. Avatar for ViJay7019 3. ViJay7019 Lv 1 97 pts. 12,776
  4. Avatar for Bletchley Park 4. Bletchley Park Lv 1 95 pts. 12,751
  5. Avatar for pauldunn 5. pauldunn Lv 1 93 pts. 12,731
  6. Avatar for christioanchauvin 6. christioanchauvin Lv 1 91 pts. 12,714
  7. Avatar for Timo van der Laan 7. Timo van der Laan Lv 1 89 pts. 12,695
  8. Avatar for Close At Hand 8. Close At Hand Lv 1 87 pts. 12,681
  9. Avatar for BootsMcGraw 9. BootsMcGraw Lv 1 86 pts. 12,666
  10. Avatar for stg123123 10. stg123123 Lv 1 84 pts. 12,655

Comments

beta_helix Staff Lv 1

Here is the CASP link for this Refinement target:
http://predictioncenter.org/casp10/target.cgi?id=116&view=refinement
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 87 & 110-11 are highly predicted to be in a sheet. However, the Leucine at residue 20 is predicted to be anything.
____________________

Note that we are giving you over 7 days to work on this one.
It's a large protein you have 3 templates to work with, so we hope that you will try changing the alignments on each of them.