beta_helix Staff Lv 1
This puzzle's deadline was extended due to the particularly heavy load of CASP10 puzzles this week.
595: 30 Residue Symmetric Trimer Freestyle
Closed since over 13 years ago
Intermediate Overall Design SymmetrySummary
- Created
- June 27, 2012
- Expires
- Max points
- 100
This is a small (30 residue) symmetric trimer design puzzle; there will be three symmetric chains to play with. We saw some very interesting structures for the related 20 residue puzzle (Puzzle 553), but ten extra residues, and three-fold symmetry, should make this a very different challenge. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!