beta_helix Staff Lv 1
This puzzle's deadline has been extended due to the heavy load of CASP10 puzzles this week.
597: 50 Residue Symmetric Dimer Freestyle
Closed since over 13 years ago
Intermediate Overall Design SymmetrySummary
- Created
- July 10, 2012
- Expires
- Max points
- 100
This is a small (50 residue) symmetric dimer design puzzle. We saw some very interesting structures in the smaller 20 and 30 residue freestyles. Using 50 residues puts this in the realm of a full-scale protein domain, and docking large secondary structure motifs becomes more viable. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together.
