beta_helix Staff Lv 1
This puzzle's deadline has been extended due to the heavy load of CASP10 puzzles this week.
597: 50 Residue Symmetric Dimer Freestyle
Closed since almost 14 years ago
Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Overall Overall Overall Overall Overall Overall Overall Overall Overall Design Design Design Design Design Design Design Design Design Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry SymmetrySummary
- Created
- July 10, 2012
- Expires
- Max points
- 100
This is a small (50 residue) symmetric dimer design puzzle. We saw some very interesting structures in the smaller 20 and 30 residue freestyles. Using 50 residues puts this in the realm of a full-scale protein domain, and docking large secondary structure motifs becomes more viable. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together.
