609 (<150): Beginner CASP10 Refinement Puzzle: TR696

Closed since over 13 years ago

Summary

• Created: July 31, 2012
• Expires: August 08, 2012 at 12:00 UTC
• Max points: 100

Description

This is the nineteenth CASP10 Refinement Target. This model was the best server prediction for target T0696, generated by the Bilab-Enable server. We've been told that ~71% of this model matches the native, so you just need to find which 29% to refine! Luckily, this is a short target with only 100 residues. More info in the puzzle comments.

Top groups

• 1. SETIKAH@KOREA 100 pts. 10,135
• 2. Gargleblasters 60 pts. 10,077
• 3. Brony@Home 33 pts. 9,902
• 4. Team Canada 17 pts. 9,842
• 5. Boinc.be 8 pts. 9,826
• 6. L'Alliance Francophone 4 pts. 9,587
• 7. Geekdo 2 pts. 9,351
• 8. Skeptics Guide to the Universe 1 pt. 9,302
• 9. DSN @ Home 1 pt. 9,208
• 10. Go Science 1 pt. 7,603

Top soloists

• 1. gardenpea 100 pts. 10,135
• 2. Jpilkington 94 pts. 10,077
• 3. sqrt 88 pts. 10,054
• 4. Pagdzin 83 pts. 9,902
• 5. theguz 78 pts. 9,899
• 6. Bearpaw 73 pts. 9,842
• 7. Perzik 68 pts. 9,826
• 8. GenGF 63 pts. 9,755
• 9. Clewi 59 pts. 9,692
• 10. Tac1 55 pts. 9,671

Comments

[beta_helix]

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=196

Note that the organizers gave us this hint:

"Starting model GDT_TS=71."

GDT_TS=71 essentially means that ONLY 71% of the model superimposes correctly onto the native structure:

en.wikipedia.org

Global distance test

The global distance test (GDT), also written as GDT_TS to represent "total score", is a measure of similarity between two protein structures with known amino acid correspondences (e.g. identical amino acid sequences) but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography, protein NMR, or, increasingly, cryoelectron microscopy. The metric was developed by Ada...