Placeholder image of a protein
Icon representing a puzzle

616: Symmetric Beta Core Design Puzzle 2

Closed since over 13 years ago

Intermediate Overall Design Symmetry

Summary

Created
August 10, 2012
Expires
Max points
100
Description

This is part two of the small symmetric dimer design puzzle that uses a known structure as a starting point. We're interested to see what sort of designs you can come up with that respect the dimer symmetry, and fold around a central beta sheet. For the previous WXCXW puzzle we gave you an extended 20 residue chain at the C-terminus. We’ve moved that chain to the N terminus for this puzzle, which should allow for very different sorts of designs. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together!

Top groups

  1. Avatar for Structuralists 31. Structuralists 1 pt. 8,581
  2. Avatar for xkcd 32. xkcd 1 pt. 8,498
  3. Avatar for null pointer exception 33. null pointer exception 1 pt. 8,426
  1. Avatar for jakbinimbol 21. jakbinimbol Lv 1 71 pts. 9,711
  2. Avatar for mimi 22. mimi Lv 1 70 pts. 9,710
  3. Avatar for meatexplosion 23. meatexplosion Lv 1 68 pts. 9,709
  4. Avatar for Schleicher 24. Schleicher Lv 1 67 pts. 9,706
  5. Avatar for krulon 25. krulon Lv 1 66 pts. 9,698
  6. Avatar for Galaxie 26. Galaxie Lv 1 65 pts. 9,697
  7. Avatar for BootsMcGraw 27. BootsMcGraw Lv 1 64 pts. 9,696
  8. Avatar for marie_s 28. marie_s Lv 1 62 pts. 9,695
  9. Avatar for caglar 29. caglar Lv 1 61 pts. 9,693
  10. Avatar for mat747 30. mat747 Lv 1 60 pts. 9,693

Comments