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623: 40 Residue Symmetric Trimer Freestyle

Closed since almost 14 years ago

Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Overall Overall Overall Overall Overall Overall Overall Overall Overall Design Design Design Design Design Design Design Design Design Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry

Summary


Created
August 27, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. We saw some very interesting structures for the related 30 residue puzzle (Puzzle 595), but ten extra residues should make this a very different challenge. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

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