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631: Electron Density Puzzle 10

Closed since over 13 years ago

Intermediate Overall Prediction Electron Density

Summary

Created
September 19, 2012
Expires
Max points
100
Description

In this electron density puzzle, we're starting you with an extended chain. You'll have to use the electron density as a guide in order to find the correct fold. Try to find the best fit for the protein inside of the guide, while still maintaining a good fold. We have posted the secondary structure predictions in the puzzle comments and put them on the starting extended chain. Get started by completing the electron density intro level (5-3).

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Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 7 & 68 are highly predicted to be part of a helix. However, the Valines at residues 31, 35, 43, 52, 88, 97, 101 & 120 are highly predicted to be in a sheet.