635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

• Created: September 27, 2012
• Expires: October 06, 2012 at 19:00 UTC
• Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

• 11. Deleted group pts. 10,311
• 12. Gargleblasters 21 pts. 10,308
• 13. Richard Dawkins Foundation 17 pts. 10,223
• 14. SETI.Germany 15 pts. 10,209
• 15. Russian team 12 pts. 10,206
• 16. FoldIt@Netherlands 10 pts. 10,134
• 17. Deleted group pts. 10,104
• 18. Friday Lab 7 pts. 10,045
• 19. Nerdfighters 6 pts. 10,008
• 20. Deleted group pts. 10,002

Top soloists

• 121. cbwest 15 pts. 9,937
• 122. Pagdzin 15 pts. 9,937
• 123. Merf 15 pts. 9,924
• 124. ViJay7019 14 pts. 9,915
• 125. bobcat 14 pts. 9,910
• 126. montadar 14 pts. 9,894
• 127. DrMistry 13 pts. 9,894
• 128. Ben666 13 pts. 9,887
• 129. Celegon 13 pts. 9,885
• 130. Roman Estep 13 pts. 9,855

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).