Foldit

635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

Created: September 27, 2012
Expires: October 06, 2012 at 19:00 UTC
Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

11. Deleted group pts. 10,311
12. Gargleblasters 21 pts. 10,308
13. Richard Dawkins Foundation 17 pts. 10,223
14. SETI.Germany 15 pts. 10,209
15. Russian team 12 pts. 10,206
16. FoldIt@Netherlands 10 pts. 10,134
17. Deleted group pts. 10,104
18. Friday Lab 7 pts. 10,045
19. Nerdfighters 6 pts. 10,008
20. Deleted group pts. 10,002

141. WBarme1234 Lv 1 10 pts. 9,738
142. kikica Lv 1 10 pts. 9,736
143. darioarena Lv 1 10 pts. 9,709
144. justjustin Lv 1 10 pts. 9,707
145. Schleicher Lv 1 9 pts. 9,685
146. Xyaneon Lv 1 9 pts. 9,661
147. Eolindel Lv 1 9 pts. 9,656
148. nemo7731 Lv 1 9 pts. 9,641
149. KingFrog Lv 1 9 pts. 9,640
150. mirjamvandelft Lv 1 9 pts. 9,629

Comments

beta_helix Staff Lv 1

September 27, 2012

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).