Foldit

639: De-novo Freestyle 17

Closed since over 13 years ago

Summary

Created: October 10, 2012
Expires: October 18, 2012 at 08:00 UTC
Max points: 100

Description

This currently unsolved short protein does not have any templates that we can use, so to prepare for CASP ROLL we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups

11. FoldIt@Netherlands 15 pts. 10,280
12. Russian team 12 pts. 10,279
13. Freedom Folders 9 pts. 10,266
14. Richard Dawkins Foundation 7 pts. 10,253
15. Foldit UK 5 pts. 10,230
16. HMT heritage 4 pts. 10,170
17. Curtin Crowd 3 pts. 10,035
18. Nerdfighters 2 pts. 9,965
19. SETI.Germany 2 pts. 9,815
20. Eὕρηκα! Heureka! 1 pt. 9,610

121. tallguy-13088 Lv 1 11 pts. 9,884
122. Jpilkington Lv 1 11 pts. 9,859
123. Dyack Lv 1 11 pts. 9,853
124. Roman Estep Lv 1 10 pts. 9,847
125. Museka Lv 1 10 pts. 9,844
126. Merf Lv 1 10 pts. 9,842
127. Tony Origami Lv 1 10 pts. 9,823
128. Bautho Lv 1 10 pts. 9,815
129. Origami314 Lv 1 9 pts. 9,810
130. Dolichwier Lv 1 9 pts. 9,774

Comments

beta_helix Staff Lv 1

October 10, 2012

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 85 & 44 are highly predicted to be part of a sheet. However, the Valines at residues 12 & 102 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).