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639: De-novo Freestyle 17

Closed since over 13 years ago

Advanced Advanced Overall Overall Prediction Prediction

Summary

Created
October 10, 2012
Expires
Max points
100
Description

This currently unsolved short protein does not have any templates that we can use, so to prepare for CASP ROLL we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

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Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 85 & 44 are highly predicted to be part of a sheet. However, the Valines at residues 12 & 102 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).