Placeholder image of a protein
Icon representing a puzzle

639: De-novo Freestyle 17

Closed since over 13 years ago

Advanced Overall Prediction

Summary

Created
October 10, 2012
Expires
Max points
100
Description

This currently unsolved short protein does not have any templates that we can use, so to prepare for CASP ROLL we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups

  1. Avatar for FoldIt@Netherlands 11. FoldIt@Netherlands 15 pts. 10,280
  2. Avatar for Russian team 12. Russian team 12 pts. 10,279
  3. Avatar for Freedom Folders 13. Freedom Folders 9 pts. 10,266
  4. Avatar for Richard Dawkins Foundation 14. Richard Dawkins Foundation 7 pts. 10,253
  5. Avatar for Foldit UK 15. Foldit UK 5 pts. 10,230
  6. Avatar for HMT heritage 16. HMT heritage 4 pts. 10,170
  7. Avatar for Curtin Crowd 17. Curtin Crowd 3 pts. 10,035
  8. Avatar for Nerdfighters 18. Nerdfighters 2 pts. 9,965
  9. Avatar for SETI.Germany 19. SETI.Germany 2 pts. 9,815
  10. Avatar for Eὕρηκα! Heureka! 20. Eὕρηκα! Heureka! 1 pt. 9,610
  1. Avatar for justjustin 261. justjustin Lv 1 1 pt. 7,891
  2. Avatar for praguequest 262. praguequest Lv 1 1 pt. 7,888
  3. Avatar for oaks 263. oaks Lv 1 1 pt. 7,863
  4. Avatar for zbaumer 264. zbaumer Lv 1 1 pt. 7,861
  5. Avatar for Worlder 265. Worlder Lv 1 1 pt. 7,827
  6. Avatar for Cerzax 266. Cerzax Lv 1 1 pt. 7,789
  7. Avatar for YDemirkol 267. YDemirkol Lv 1 1 pt. 7,759
  8. Avatar for joeygforce 268. joeygforce Lv 1 1 pt. 7,757
  9. Avatar for greepski 269. greepski Lv 1 1 pt. 7,717
  10. Avatar for itamar.gru 270. itamar.gru Lv 1 1 pt. 7,702

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 85 & 44 are highly predicted to be part of a sheet. However, the Valines at residues 12 & 102 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).