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656: 40 Residue Symmetric Trimer Retry

Closed since over 13 years ago

Advanced Advanced Advanced Advanced Advanced Advanced Advanced Advanced Advanced Overall Overall Overall Overall Overall Overall Overall Overall Overall Design Design Design Design Design Design Design Design Design Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry

Summary

Created
November 21, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. It is the same as 623 except the Residue Interaction Energy filter is enabled. This filter will give a score bonus or penalty based on how well your residues are scoring compared to expected values.

Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

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Comments

bertro Lv 1

Are you sure the Residue Interaction Energy filter is enabled? Because I see lots of Tryptophans in my solution.

tamirh Lv 1

Below your score there should be an arrow plus something that says "No bonuses, no penalties., all conditions met" (ignore the mis-punctuation) and click on the arrow.

You can click "Show" to see where (if any) of your residues are not scoring well through the Residue IE filter.

tamirh Lv 1

If you upload a screenshot I can try to explain any seemingly odd behavior (or more likely I will ask one of the scientists).

bertro Lv 1

There is nothing that shows and there are no penalties either. The message in blue says "Residue IE Score met(REQUIRED)

I have 11 Tryptophans in my solution so far.

Sorry no facility to upload a screenshot here (unlike the feedback pages).