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656: 40 Residue Symmetric Trimer Retry

Closed since over 13 years ago

Advanced Overall Design Symmetry

Summary

Created
November 21, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. It is the same as 623 except the Residue Interaction Energy filter is enabled. This filter will give a score bonus or penalty based on how well your residues are scoring compared to expected values.

Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

Top groups

  1. Avatar for Team Canada 21. Team Canada 1 pt. 10,081
  2. Avatar for Mojo Risin' 22. Mojo Risin' 1 pt. 9,661
  3. Avatar for Deleted group 23. Deleted group pts. 9,500
  4. Avatar for Atheists, Skeptics, & Humanists 24. Atheists, Skeptics, & Humanists 1 pt. 9,462
  5. Avatar for null pointer exception 25. null pointer exception 1 pt. 8,225
  6. Avatar for Richard Dawkins Foundation 26. Richard Dawkins Foundation 1 pt. 0
  7. Avatar for DSN @ Home 27. DSN @ Home 1 pt. 0
  1. Avatar for doug.ehlert
    1. doug.ehlert Lv 1
    100 pts. 13,277
  2. Avatar for Schleicher 2. Schleicher Lv 1 99 pts. 13,189
  3. Avatar for stg123123 3. stg123123 Lv 1 97 pts. 12,869
  4. Avatar for Bletchley Park 4. Bletchley Park Lv 1 96 pts. 12,861
  5. Avatar for Ch Garnier 5. Ch Garnier Lv 1 94 pts. 12,768
  6. Avatar for spdenne 6. spdenne Lv 1 93 pts. 12,749
  7. Avatar for martinzblavy 7. martinzblavy Lv 1 91 pts. 12,705
  8. Avatar for frood66 8. frood66 Lv 1 90 pts. 12,651
  9. Avatar for karstenw 9. karstenw Lv 1 88 pts. 12,642
  10. Avatar for smilingone 10. smilingone Lv 1 87 pts. 12,621

Comments

bertro Lv 1

Are you sure the Residue Interaction Energy filter is enabled? Because I see lots of Tryptophans in my solution.

tamirh Lv 1

Below your score there should be an arrow plus something that says "No bonuses, no penalties., all conditions met" (ignore the mis-punctuation) and click on the arrow.

You can click "Show" to see where (if any) of your residues are not scoring well through the Residue IE filter.

tamirh Lv 1

If you upload a screenshot I can try to explain any seemingly odd behavior (or more likely I will ask one of the scientists).

bertro Lv 1

There is nothing that shows and there are no penalties either. The message in blue says "Residue IE Score met(REQUIRED)

I have 11 Tryptophans in my solution so far.

Sorry no facility to upload a screenshot here (unlike the feedback pages).