Placeholder image of a protein
Icon representing a puzzle

656: 40 Residue Symmetric Trimer Retry

Closed since over 13 years ago

Advanced Advanced Advanced Advanced Advanced Advanced Advanced Advanced Advanced Overall Overall Overall Overall Overall Overall Overall Overall Overall Design Design Design Design Design Design Design Design Design Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry

Summary

Created
November 21, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. It is the same as 623 except the Residue Interaction Energy filter is enabled. This filter will give a score bonus or penalty based on how well your residues are scoring compared to expected values.

Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

Top groups

  1. Avatar for Team Canada 21. Team Canada 1 pt. 10,081
  2. Avatar for Mojo Risin' 22. Mojo Risin' 1 pt. 9,661
  3. Avatar for Deleted group 23. Deleted group pts. 9,500
  4. Avatar for Atheists, Skeptics, & Humanists 24. Atheists, Skeptics, & Humanists 1 pt. 9,462
  5. Avatar for null pointer exception 25. null pointer exception 1 pt. 8,225
  6. Avatar for Richard Dawkins Foundation 26. Richard Dawkins Foundation 1 pt. 0
  7. Avatar for DSN @ Home 27. DSN @ Home 1 pt. 0
  1. Avatar for doug.ehlert
    1. doug.ehlert Lv 1
    100 pts. 13,277
  2. Avatar for Schleicher 2. Schleicher Lv 1 99 pts. 13,189
  3. Avatar for stg123123 3. stg123123 Lv 1 97 pts. 12,869
  4. Avatar for Bletchley Park 4. Bletchley Park Lv 1 96 pts. 12,861
  5. Avatar for Ch Garnier 5. Ch Garnier Lv 1 94 pts. 12,768
  6. Avatar for spdenne 6. spdenne Lv 1 93 pts. 12,749
  7. Avatar for martinzblavy 7. martinzblavy Lv 1 91 pts. 12,705
  8. Avatar for frood66 8. frood66 Lv 1 90 pts. 12,651
  9. Avatar for karstenw 9. karstenw Lv 1 88 pts. 12,642
  10. Avatar for smilingone 10. smilingone Lv 1 87 pts. 12,621

Comments

bertro Lv 1

Are you sure the Residue Interaction Energy filter is enabled? Because I see lots of Tryptophans in my solution.

tamirh Lv 1

Below your score there should be an arrow plus something that says "No bonuses, no penalties., all conditions met" (ignore the mis-punctuation) and click on the arrow.

You can click "Show" to see where (if any) of your residues are not scoring well through the Residue IE filter.

tamirh Lv 1

If you upload a screenshot I can try to explain any seemingly odd behavior (or more likely I will ask one of the scientists).

bertro Lv 1

There is nothing that shows and there are no penalties either. The message in blue says "Residue IE Score met(REQUIRED)

I have 11 Tryptophans in my solution so far.

Sorry no facility to upload a screenshot here (unlike the feedback pages).