Placeholder image of a protein
Icon representing a puzzle

656: 40 Residue Symmetric Trimer Retry

Closed since over 13 years ago

Advanced Overall Design Symmetry

Summary

Created
November 21, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. It is the same as 623 except the Residue Interaction Energy filter is enabled. This filter will give a score bonus or penalty based on how well your residues are scoring compared to expected values.

Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 13,277
  2. Avatar for SETI.Germany 2. SETI.Germany 83 pts. 13,189
  3. Avatar for Beta Folders 3. Beta Folders 68 pts. 12,881
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 55 pts. 12,823
  5. Avatar for Void Crushers 5. Void Crushers 44 pts. 12,774
  6. Avatar for Gargleblasters 6. Gargleblasters 35 pts. 12,714
  7. Avatar for Anthropic Dreams 7. Anthropic Dreams 27 pts. 12,648
  8. Avatar for Go Science 8. Go Science 21 pts. 12,614
  9. Avatar for HMT heritage 9. HMT heritage 16 pts. 12,424
  10. Avatar for Origami 2 10. Origami 2 12 pts. 12,412
  1. Avatar for FrankytheBrain 101. FrankytheBrain Lv 1 15 pts. 11,754
  2. Avatar for truestone 102. truestone Lv 1 14 pts. 11,745
  3. Avatar for martinf 103. martinf Lv 1 14 pts. 11,745
  4. Avatar for fishercat 104. fishercat Lv 1 14 pts. 11,722
  5. Avatar for harvardman 105. harvardman Lv 1 13 pts. 11,719
  6. Avatar for balb26 106. balb26 Lv 1 13 pts. 11,704
  7. Avatar for Savas 107. Savas Lv 1 13 pts. 11,698
  8. Avatar for YGK 108. YGK Lv 1 12 pts. 11,694
  9. Avatar for ComputerMage 109. ComputerMage Lv 1 12 pts. 11,692
  10. Avatar for djag 110. djag Lv 1 12 pts. 11,686

Comments

bertro Lv 1

Are you sure the Residue Interaction Energy filter is enabled? Because I see lots of Tryptophans in my solution.

tamirh Lv 1

Below your score there should be an arrow plus something that says "No bonuses, no penalties., all conditions met" (ignore the mis-punctuation) and click on the arrow.

You can click "Show" to see where (if any) of your residues are not scoring well through the Residue IE filter.

tamirh Lv 1

If you upload a screenshot I can try to explain any seemingly odd behavior (or more likely I will ask one of the scientists).

bertro Lv 1

There is nothing that shows and there are no penalties either. The message in blue says "Residue IE Score met(REQUIRED)

I have 11 Tryptophans in my solution so far.

Sorry no facility to upload a screenshot here (unlike the feedback pages).