Placeholder image of a protein
Icon representing a puzzle

659: Re-Return of the Tissue Regeneration Design Puzzle

Closed since over 13 years ago

Intermediate Overall Design

Summary

Created
December 05, 2012
Expires
Max points
100
Description

We are giving you a 10 residue helix positioned over a hydrophobic groove where binding occurs in nature. This native binding region in marked by unfrozen side chains. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle. More details in the puzzle comments.

Top groups

  1. Avatar for Beta Folders
    1. Beta Folders
    100 pts. 9,361
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 85 pts. 9,359
  3. Avatar for Go Science 3. Go Science 72 pts. 9,359
  4. Avatar for Contenders 4. Contenders 61 pts. 9,358
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 51 pts. 9,357
  6. Avatar for foldeRNA 6. foldeRNA 42 pts. 9,323
  7. Avatar for Void Crushers 7. Void Crushers 35 pts. 9,317
  8. Avatar for Deleted group 8. Deleted group pts. 9,315
  9. Avatar for SETI.Germany 9. SETI.Germany 23 pts. 9,313
  10. Avatar for Gargleblasters 10. Gargleblasters 19 pts. 9,311
  1. Avatar for SnoopySnoopy 281. SnoopySnoopy Lv 1 1 pt. 9,153
  2. Avatar for donak 282. donak Lv 1 1 pt. 9,152
  3. Avatar for Hannah42 283. Hannah42 Lv 1 1 pt. 9,149
  4. Avatar for colton1232 284. colton1232 Lv 1 1 pt. 9,149
  5. Avatar for ruusky 285. ruusky Lv 1 1 pt. 9,148
  6. Avatar for wtketch 286. wtketch Lv 1 1 pt. 9,147
  7. Avatar for MCB555_pmcgurrin 287. MCB555_pmcgurrin Lv 1 1 pt. 9,147
  8. Avatar for johngran 288. johngran Lv 1 1 pt. 9,146
  9. Avatar for MCBNEU555Zhao 289. MCBNEU555Zhao Lv 1 1 pt. 9,146
  10. Avatar for kev53846 290. kev53846 Lv 1 1 pt. 9,145

Comments

tamirh Lv 1

This is a repost of Puzzle 571: Tissue Regeneration Design Puzzle, but with a new filter that should help with the scoring artifacts that were prevalent in that puzzle. We tried this with puzzle 633 but the ResidueIE filter was broken and this caused windows machines to crash. With the ResidueIE filter fixed, we wanted to try the puzzle again.

More background on this puzzle can be found in the original blogpost: http://fold.it/portal/node/992888