Placeholder image of a protein
Icon representing a puzzle

664: Unlocked Frizzled Design Puzzle

Closed since about 13 years ago

Beginner Overall Design

Summary

Created
December 29, 2012
Expires
Max points
100
Description

This is a the same protein as Puzzle 640 (Frizzled with a wider pocket than Puzzle 659) but this time the helix is unlocked. You can mutate any residue on the helix but none on Frizzled. We still have the new "Residue Interaction Energy" filter. Natural proteins avoid putting Tryptophan, Phenylalanine, and Tyrosine on the surface. However, Foldit often gives a score bonus if you load up the surface of your design with Tryptophan. The ResidueIE filter helps to counteract that, helping you make more useful designs. More details in the puzzle comments.

Top groups

  1. Avatar for Skeptics Guide to the Universe 31. Skeptics Guide to the Universe 1 pt. 10,108
  2. Avatar for Deleted group 32. Deleted group pts. 10,085
  3. Avatar for sjmp 33. sjmp 1 pt. 9,978
  4. Avatar for Deleted group 34. Deleted group pts. 9,710
  5. Avatar for test_group1 35. test_group1 1 pt. 9,710
  6. Avatar for Window Group 36. Window Group 1 pt. 9,710
  1. Avatar for drjr 11. drjr Lv 1 86 pts. 10,251
  2. Avatar for jakbinimbol 12. jakbinimbol Lv 1 84 pts. 10,249
  3. Avatar for Bushman 13. Bushman Lv 1 83 pts. 10,247
  4. Avatar for hpaege 14. hpaege Lv 1 81 pts. 10,246
  5. Avatar for Roman Estep 15. Roman Estep Lv 1 80 pts. 10,244
  6. Avatar for doug.ehlert 16. doug.ehlert Lv 1 79 pts. 10,243
  7. Avatar for martinzblavy 17. martinzblavy Lv 1 78 pts. 10,242
  8. Avatar for fable 18. fable Lv 1 76 pts. 10,242
  9. Avatar for O Seki To 19. O Seki To Lv 1 75 pts. 10,242
  10. Avatar for Grom 20. Grom Lv 1 74 pts. 10,238

Comments