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702: Second Sepsis Puzzle Round 2

Closed since almost 13 years ago

Intermediate Overall Design

Summary

Created
April 17, 2013
Expires
Max points
100
Description

This is Round 2 for Puzzle 697. You will be able to load in your manual saves from 697 and use them as a starting point here. This puzzle has been opened up to allow for sharing and the use of all scripts. See if you can improve your model from the first round using these tools, or start from scratch! NOTE: If you did not manually save a solution in puzzle 697, you can go back to 697, manually save it, and the solution should appear in your manual saves for this puzzle. PLEASE NOTICE that Valine 32 can be mutated!

Top groups

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  7. Avatar for SETIKAH@KOREA 17. SETIKAH@KOREA 1 pt. 8,504
  8. Avatar for University of Washington 18. University of Washington 1 pt. 8,504
  9. Avatar for Team Toombs 19. Team Toombs 1 pt. 8,494
  10. Avatar for Androids 20. Androids 1 pt. 8,478
  1. Avatar for Museka 11. Museka Lv 1 83 pts. 9,526
  2. Avatar for alcor29 12. alcor29 Lv 1 81 pts. 9,512
  3. Avatar for Timo van der Laan 13. Timo van der Laan Lv 1 79 pts. 9,504
  4. Avatar for Steve001 14. Steve001 Lv 1 78 pts. 9,489
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  6. Avatar for markm457 16. markm457 Lv 1 75 pts. 9,431
  7. Avatar for pvc78 17. pvc78 Lv 1 73 pts. 9,417
  8. Avatar for jakbinimbol 18. jakbinimbol Lv 1 72 pts. 9,404
  9. Avatar for Galaxie 19. Galaxie Lv 1 70 pts. 9,378
  10. Avatar for nemo7731 20. nemo7731 Lv 1 69 pts. 9,354

Comments

beta_helix Staff Lv 1

Please read the Blog Entry about this puzzle: http://fold.it/portal/node/994592

and here is a link to the Scientist Chat about it:
http://fold.it/portal/node/994944

PLEASE NOTE that Valine 32 can be mutated!
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If you are new to Foldit, make sure you have completed Intro Puzzles 7-1 through 7-4 before trying this puzzle.
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This puzzle has the ResidueIE filter on (to try to ensure that PHE, TYR, and TRP residues are scoring properly) and we've increased the Ligand Score by a factor of 10 to promote interactions with the sugar.

Tip: To see the parts of the sugar that you can bond to, check Show bonds (non-protein) and Show bondable atoms in the View menu. Make sure Show bonds (loop) and Show bonds (sidechain) are also on. Blue can bond to red, and purple can bond to either blue or red.