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702: Second Sepsis Puzzle Round 2

Closed since almost 13 years ago

Intermediate Overall Design

Summary

Created
April 17, 2013
Expires
Max points
100
Description

This is Round 2 for Puzzle 697. You will be able to load in your manual saves from 697 and use them as a starting point here. This puzzle has been opened up to allow for sharing and the use of all scripts. See if you can improve your model from the first round using these tools, or start from scratch! NOTE: If you did not manually save a solution in puzzle 697, you can go back to 697, manually save it, and the solution should appear in your manual saves for this puzzle. PLEASE NOTICE that Valine 32 can be mutated!

Top groups

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    1. Anthropic Dreams
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  4. Avatar for Contenders 4. Contenders 53 pts. 9,642
  5. Avatar for Deleted group 5. Deleted group pts. 9,561
  6. Avatar for Void Crushers 6. Void Crushers 33 pts. 9,504
  7. Avatar for Gargleblasters 7. Gargleblasters 26 pts. 9,458
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  10. Avatar for SETI.Germany 10. SETI.Germany 11 pts. 9,175
  1. Avatar for steveB 41. steveB Lv 1 44 pts. 9,087
  2. Avatar for drjr 42. drjr Lv 1 43 pts. 9,065
  3. Avatar for KingLear 43. KingLear Lv 1 42 pts. 9,062
  4. Avatar for grogar7 44. grogar7 Lv 1 41 pts. 9,055
  5. Avatar for Aubade00 45. Aubade00 Lv 1 40 pts. 9,054
  6. Avatar for cobaltteal 46. cobaltteal Lv 1 39 pts. 9,034
  7. Avatar for eromana 47. eromana Lv 1 38 pts. 9,033
  8. Avatar for marie_s 48. marie_s Lv 1 37 pts. 9,025
  9. Avatar for BootsMcGraw 49. BootsMcGraw Lv 1 36 pts. 9,024
  10. Avatar for spvincent 50. spvincent Lv 1 35 pts. 9,017

Comments

beta_helix Staff Lv 1

Please read the Blog Entry about this puzzle: http://fold.it/portal/node/994592

and here is a link to the Scientist Chat about it:
http://fold.it/portal/node/994944

PLEASE NOTE that Valine 32 can be mutated!
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If you are new to Foldit, make sure you have completed Intro Puzzles 7-1 through 7-4 before trying this puzzle.
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This puzzle has the ResidueIE filter on (to try to ensure that PHE, TYR, and TRP residues are scoring properly) and we've increased the Ligand Score by a factor of 10 to promote interactions with the sugar.

Tip: To see the parts of the sugar that you can bond to, check Show bonds (non-protein) and Show bondable atoms in the View menu. Make sure Show bonds (loop) and Show bonds (sidechain) are also on. Blue can bond to red, and purple can bond to either blue or red.