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709: De-novo Freestyle 24: Hand-folding Round

Closed since almost 13 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
May 04, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein (this one doesn't have any homologs) as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

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Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 109 is highly predicted to be part of a helix. However, the Valine at residue 139 is predicted to be in a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.