Placeholder image of a protein
Icon representing a puzzle

709: De-novo Freestyle 24: Hand-folding Round

Closed since almost 13 years ago

Intermediate Intermediate Overall Overall Prediction Prediction Hand-Folding Hand-Folding

Summary


Created
May 04, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein (this one doesn't have any homologs) as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Richard Dawkins Foundation 11. Richard Dawkins Foundation 13 pts. 10,446
  2. Avatar for SETI.Germany 12. SETI.Germany 10 pts. 10,392
  3. Avatar for Russian team 13. Russian team 7 pts. 10,225
  4. Avatar for Natural Abilities 14. Natural Abilities 6 pts. 10,182
  5. Avatar for Deleted group 15. Deleted group pts. 10,168
  6. Avatar for It's over 9000! 16. It's over 9000! 3 pts. 9,974
  7. Avatar for HMT heritage 17. HMT heritage 2 pts. 9,675
  8. Avatar for Team Toombs 19. Team Toombs 1 pt. 8,810

  1. Avatar for Reinderien 171. Reinderien Lv 1 1 pt. 8,810
  2. Avatar for magdrog 172. magdrog Lv 1 1 pt. 8,803
  3. Avatar for Incongruous 173. Incongruous Lv 1 1 pt. 8,763
  4. Avatar for Lindata 174. Lindata Lv 1 1 pt. 8,736
  5. Avatar for pstaff2 175. pstaff2 Lv 1 1 pt. 8,725
  6. Avatar for JDScienceTeacher 176. JDScienceTeacher Lv 1 1 pt. 8,708
  7. Avatar for Duncan Kirby 177. Duncan Kirby Lv 1 1 pt. 8,589
  8. Avatar for heyubob 178. heyubob Lv 1 1 pt. 8,567
  9. Avatar for thepuzzleman 179. thepuzzleman Lv 1 1 pt. 8,566
  10. Avatar for Psych0Active 180. Psych0Active Lv 1 1 pt. 8,551

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 109 is highly predicted to be part of a helix. However, the Valine at residue 139 is predicted to be in a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.