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720: Quick Puzzle: 76 Residue Dimer

Closed since almost 13 years ago

Summary

Created: May 28, 2013
Expires: May 31, 2013 at 23:59 UTC
Max points: 100

Description

This is 76 residue symmetric dimer design puzzle, much like Puzzle 708. There are two flters enabled on this puzzle. The ResidueIE filter ensures PHY, TYR, and TRP residues are scoring well. The "Core Exists" filter ensures the number of residues in the core is at least 30%. We're starting you with johnmitch's monomer solution to Puzzle 687, but we've mutated all residues to isoleucine. You'll have to make your own mutations and design a well-packed dimer interface to increase your score. This is just a starting point, of course; you are free to redesign the entire protein in this puzzle.