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764: 45 Residue Pentamer Design

Closed since over 12 years ago

Intermediate Overall Design Symmetry

Summary


Created
August 19, 2013
Expires
Max points
100
Description

This is a 45 residue symmetric pentamer design puzzle; there will be five symmetric chains to manage. Note that the score of a symmetric protein relies not only on how well-folded each chain is, but also on how well the chains interface together. See the blog post about this for more information. There are 2 filters enabled on this puzzle: the Residue IE Score monitors that all PHY, TYR, and TRP residues are scoring well, and the Core Exists filter checks that at least 30% of the residues are buried in the core of your design. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions.

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Comments


retiredmichael Lv 1

not loading properly, when I try to load my point total is 10785 not 11025. tried on two different computers same result.