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769: Quick Loop Redesign

Closed since over 12 years ago

Intermediate Intermediate Overall Overall Design Design

Summary

Created: August 27, 2013
Expires: August 30, 2013 at 20:00 UTC
Max points: 100

Description

This is a puzzle where you can redesign part of a player-designed protein. This is the subunit of a symmetric tetramer designed by jamiexq, karstenw, and markm457 for Puzzle 725. Baker lab simulations suggest that one of the beta strands is unlikely to form because the loops on either end prefer different conformations. Help us redesign these loops to find a solution that will fold up properly! You have one additional residue that you can insert in the protein, but most of the protein is frozen in this puzzle. This puzzle will only be active for three days!