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769: Quick Loop Redesign

Closed since over 12 years ago

Intermediate Overall Design

Summary


Created
August 27, 2013
Expires
Max points
100
Description

This is a puzzle where you can redesign part of a player-designed protein. This is the subunit of a symmetric tetramer designed by jamiexq, karstenw, and markm457 for Puzzle 725. Baker lab simulations suggest that one of the beta strands is unlikely to form because the loops on either end prefer different conformations. Help us redesign these loops to find a solution that will fold up properly! You have one additional residue that you can insert in the protein, but most of the protein is frozen in this puzzle. This puzzle will only be active for three days!

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