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802: Revisiting Puzzle 686: Black Belt De-novo

Closed since over 12 years ago

Intermediate Overall Prediction

Summary


Created
October 30, 2013
Expires
Max points
100
Description

This is a repost of Puzzle 686. When this puzzle ran in March of this year, the structure of this protein was still unknown. Now the structure has been published, and we're making the puzzle available for the Black Belt Folding broadcast this weekend! This puzzle will be used during the Black Belt Folding session, so take some time to familiarize yourself with the puzzle ahead of time. Players will NOT be able to load in any previous solutions for these puzzles.

Top groups


  1. Avatar for Deleted group 21. Deleted group pts. 8,665
  2. Avatar for test_group1 22. test_group1 1 pt. 8,580
  3. Avatar for Czech National Team 24. Czech National Team 1 pt. 8,339
  4. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,225
  5. Avatar for Hydrophobic Helpers 26. Hydrophobic Helpers 1 pt. 7,087

  1. Avatar for foldthestuffman 171. foldthestuffman Lv 1 1 pt. 8,951
  2. Avatar for Mikayla.Caudwell 172. Mikayla.Caudwell Lv 1 1 pt. 8,940
  3. Avatar for troy gittos 173. troy gittos Lv 1 1 pt. 8,915
  4. Avatar for Arne Heessels 174. Arne Heessels Lv 1 1 pt. 8,904
  5. Avatar for Deleted player 175. Deleted player pts. 8,899
  6. Avatar for MalcolmW 176. MalcolmW Lv 1 1 pt. 8,880
  7. Avatar for Lindata 177. Lindata Lv 1 1 pt. 8,864
  8. Avatar for relaxmax 178. relaxmax Lv 1 1 pt. 8,834
  9. Avatar for Zepp 179. Zepp Lv 1 1 pt. 8,824
  10. Avatar for galactobourico 180. galactobourico Lv 1 1 pt. 8,817

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 25 & 58 are highly predicted to be part of a sheet. However, the Alanines at residues 40 & 47 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.