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860: 72 Residue Monomer Design

Closed since almost 12 years ago

Intermediate Overall Design

Summary


Created
March 14, 2014
Expires
Max points
100
Description

This is a single-chain design puzzle with 72 residues. This puzzle is similar to Puzzle 854, with a few key changes: the Core Exists filter requirement has been relaxed and may allow more "adventuresome" designs; in addition, the Fragment Filter has been omitted, although it may return in a followup refinement round. As usual, the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups


  1. Avatar for Eὕρηκα! Heureka! 22. Eὕρηκα! Heureka! 1 pt. 7,801
  2. Avatar for Czech National Team 23. Czech National Team 1 pt. 7,772
  3. Avatar for Crunching Family 24. Crunching Family 1 pt. 7,650
  4. Avatar for Hydrophobic Helpers 25. Hydrophobic Helpers 1 pt. 7,234
  5. Avatar for DSN @ Home 26. DSN @ Home 1 pt. 7,022
  6. Avatar for Deleted group 27. Deleted group pts. 6,893
  7. Avatar for Geekdo 28. Geekdo 1 pt. 2,146
  8. Avatar for BOINC@Poland 29. BOINC@Poland 1 pt. 0
  9. Avatar for Team Germany 30. Team Germany 1 pt. 0

  1. Avatar for Bruno Kestemont 31. Bruno Kestemont Lv 1 48 pts. 9,781
  2. Avatar for Anfinsen_slept_here 32. Anfinsen_slept_here Lv 1 47 pts. 9,769
  3. Avatar for dcrwheeler 33. dcrwheeler Lv 1 46 pts. 9,763
  4. Avatar for Deleted player 34. Deleted player pts. 9,721
  5. Avatar for utaca 35. utaca Lv 1 43 pts. 9,720
  6. Avatar for bertro 36. bertro Lv 1 42 pts. 9,711
  7. Avatar for phi16 37. phi16 Lv 1 41 pts. 9,710
  8. Avatar for Blake Estep 38. Blake Estep Lv 1 40 pts. 9,707
  9. Avatar for smilingone 39. smilingone Lv 1 39 pts. 9,693
  10. Avatar for drjr 40. drjr Lv 1 38 pts. 9,668

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