860: 72 Residue Monomer Design

Closed since about 12 years ago

Summary

• Created: March 14, 2014
• Expires: March 21, 2014 at 23:00 UTC
• Max points: 100

Description

This is a single-chain design puzzle with 72 residues. This puzzle is similar to Puzzle 854, with a few key changes: the Core Exists filter requirement has been relaxed and may allow more "adventuresome" designs; in addition, the Fragment Filter has been omitted, although it may return in a followup refinement round. As usual, the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

• 1. Anthropic Dreams 100 pts. 10,081
• 2. Beta Folders 84 pts. 10,045
• 3. Russian team 70 pts. 10,011
• 4. Void Crushers 58 pts. 9,994
• 5. Go Science 48 pts. 9,976
• 6. L'Alliance Francophone 39 pts. 9,946
• 7. HMT heritage 32 pts. 9,888
• 8. Contenders 26 pts. 9,883
• 9. Gargleblasters 20 pts. 9,828
• 10. Deleted group pts. 9,769

Top evolvers

• 21. O Seki To 3 pts. 9,888
• 22. Bletchley Park 2 pts. 9,883
• 23. gitwut 2 pts. 9,881
• 24. mimi 1 pt. 9,875
• 25. histon 1 pt. 9,875
• 26. alwen 1 pt. 9,875
• 27. jamiexq 1 pt. 9,874
• 28. Antibrad 1 pt. 9,874
• 29. Jean-Bob 1 pt. 9,871
• 30. spvincent 1 pt. 9,869