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866: 85 Residue Monomer Design

Closed since about 12 years ago

Intermediate Overall Design

Summary


Created
March 27, 2014
Expires
Max points
100
Description

This is a single-chain design puzzle with 85 residues. There are 2 filters enabled on this puzzle: the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well, and the Core Existence filter checks that at least 30% of the residues are buried in the core of your design. The High Wiggle Power option has been disabled, and the Fragment Filter has been omitted, although these tools may return in a followup refinement round. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!

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