Placeholder image of a protein
Icon representing a puzzle

898b: 75 Residue Monomer Design: Weak Helices

Closed since almost 12 years ago

Intermediate Overall Design

Summary


Created
May 23, 2014
Expires
Max points
100
Description

NOTE: This is a repost of Puzzle 898, with the Fragment Filter removed.

This is a design puzzle with 75 residues and is very similar to previous design puzzles, except that helices should not score as well as they normally do. Try some new designs and see how they compete with handicapped helices! There are 2 filters enabled on this puzzle: the Residue IE Score monitors that all PHE, TYR, and TRP residues are scoring well, and the Core Existence filter checks that at least 30% of the residues are buried in the core of your design. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups


  1. Avatar for Russian team 11. Russian team 5 pts. 9,052
  2. Avatar for Deleted group 12. Deleted group pts. 8,965
  3. Avatar for HMT heritage 14. HMT heritage 2 pts. 8,834
  4. Avatar for Italiani Al Lavoro 15. Italiani Al Lavoro 1 pt. 8,543
  5. Avatar for Natural Abilities 16. Natural Abilities 1 pt. 8,496
  6. Avatar for Repro-men 18. Repro-men 1 pt. 8,392
  7. Avatar for Mojo Risin' 20. Mojo Risin' 1 pt. 8,101

  1. Avatar for Lindata 101. Lindata Lv 1 4 pts. 8,387
  2. Avatar for SouperGenious 102. SouperGenious Lv 1 3 pts. 8,386
  3. Avatar for parsnip 103. parsnip Lv 1 3 pts. 8,367
  4. Avatar for goastano 104. goastano Lv 1 3 pts. 8,353
  5. Avatar for Ch Garnier 105. Ch Garnier Lv 1 3 pts. 8,352
  6. Avatar for MaartenDesnouck 106. MaartenDesnouck Lv 1 3 pts. 8,338
  7. Avatar for reefyrob 107. reefyrob Lv 1 3 pts. 8,318
  8. Avatar for Deleted player 108. Deleted player 3 pts. 8,290
  9. Avatar for tyler0911 109. tyler0911 Lv 1 2 pts. 8,281
  10. Avatar for brgreening 110. brgreening Lv 1 2 pts. 8,275

Comments


spmm Lv 1

I am not finding any difference between low and medium wiggle power on this one.

retiredmichael Lv 1

constraints still need work, had some computer issues, so was not able to fully work the sheet array's. you could just set some rules, the folds must contain 3-5 elements 2 of which must be sheets.