We've just re-posted the 300 residue protein to devprev after making some fixes/changes to centroid.
We've also provided a Full-atom version of this 300-res protein for the sake of comparison.
Let us know if you see any bugs, and what performance differences you notice!
This is a player solution that has several bad fragments. You should be able to see the bad fragments by clicking 'show' on the filter.
The Remix tool should be available, so try and use it on the bad fragment regions to resolve them.
Any feedback on both the Fragment Filter and Remix Tool is appreciated!
This puzzle may help us figure out why so many players experienced crashes on Puzzle 814.
This is a repost of an old C2-symmetry puzzle with the new Fragment Filter and Remix Tool. Try it out with the scripts and tools that crashed Puzzle 814 and let us know how it fares!
Your feedback is welcome in the puzzle comments: http://fold.it/portal/node/996469
In response to this feedback topic, the latest devprev update includes a fix to "circumvent" the loading problem many people were seeing in the latest symmetric puzzle. Unfortunately, we're still unsure of the root cause of this bug, so we're continuing to gather information on the problem.
There's a new Broken Symmetry Loads puzzle in devprev. Please try it out, run some of the scripts you might have run on the interface redesign puzzles, save your solutions regularly and try loading them back into the client. Let us know if you continue to see the saving and loading problems you previously experienced. Your help is much appreciated!
You can post your comments on the puzzle page here: http://fold.it/portal/node/997310
We've introduced a new type of constraint in this puzzle that is more appropriate for the information in predicted contacts. Satisfied contacts contribute directly to your score and are compatible with wiggle and shake, but there is no penalty for unsatisfied contacts. We're excited to introduce this before the first predicted contacts targets of CASP11, so try it out and leave your feedback in the puzzle comments here:
http://fold.it/portal/node/997776
Thanks to all of our devprev players for helping us improve Foldit!
We've developed a new Secondary Structure filter, which measures the number of residues in helices or sheets. Rather than depending on the player-assigned secondary structure, the filter uses a DSSP algorithm to determine secondary structure based on hydrogen bonding patterns. As many of you know, Foldit naturally favors helices over other types of secondary structure, so the top-scoring Foldit designs are invariably helical bundles. This filter can limit the amount of helices in top-scoring designs, and we hope it will encourage players to explore new and different folds without having to compete with simple helical designs!
Try out the Secondary Structure Filter in the latest devprev puzzle, and leave your feedback in the puzzle comments here:
http://fold.it/portal/node/998126
Thank you!
Now that CASP is over, we'd like to start posting electron density puzzles again. There were some behind-the-scenes changes with the New Chapter update earlier this year, but we think electron density is ready to go! Try out this puzzle and let us know how it plays!
Please leave your feedback in the puzzle comments here:
http://fold.it/portal/node/1998642
Thank you!
Hi everyone, we've reposted Puzzle 1087 here for debugging purposes. We've made some changes recently so that Foldit can report a lot more debugging information with players' solutions. See if you can reproduce the scoring issues that players were having when loading in solutions, and let us know when you do! Your help in this is much appreciated!
Check out the puzzle here:
http://fold.it/portal/node/2000825
Please check out our latest devprev puzzle! It is a clone of a previous puzzle, and we just want to make sure that recent changes to the game have not affected the way Foldit displays electron density. Open up this puzzle and make sure you can interact with the density as you normally do! Please leave your feedback in the puzzle comments:
Please check out our new design puzzle in devprev. The puzzle includes two new features: a filter that grants players the ability to temporarily add "extra" residues; and a new Rama Map tool that gives players better control over individual residues. Please try out these features and let us know of any problems. Your feedback is much appreciated!
Please leave feedback in the puzzle comments:
http://fold.it/portal/node/2002161