In this category, players design new proteins for anything and everything -- from eco-friendly materials, to treatments for deadly diseases, to super-efficient enzymes. Players must design their protein so that it achieves the puzzle Objectives, and change its sequence so that the protein folds correctly.


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Recent design puzzles

Puzzle Status
Design of the Month: March 2023 Closed since almost 3 years ago
Design of the Month: February 2023 Closed since about 3 years ago
2262: FMN Ligand Binder Design: Round 7 Closed since about 3 years ago
2259: Monkeypox H3 Binder Design: Round 10 Closed since about 3 years ago
2257: FMN Ligand Binder Design: Round 6 Closed since about 3 years ago