Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for Galaxie 11. Galaxie Lv 1 1,117
  2. Avatar for Elfi 12. Elfi Lv 1 1,070
  3. Avatar for prkfour 13. prkfour Lv 1 919
  4. Avatar for AlkiP0Ps 14. AlkiP0Ps Lv 1 911
  5. Avatar for dcrwheeler 15. dcrwheeler Lv 1 886
  6. Avatar for bravosk8erboy 16. bravosk8erboy Lv 1 814
  7. Avatar for nspc 17. nspc Lv 1 630
  8. Avatar for nicobul 18. nicobul Lv 1 613
  9. Avatar for Th1sN@me!sN0tAPun 19. Th1sN@me!sN0tAPun Lv 1 594
  10. Avatar for spvincent 20. spvincent Lv 1 553

Recent small molecule design puzzles

Puzzle Status
2748: SF-1 Round 6 Open for the next about 14 hours
2745: LRH-1 Round 6 Closed since 3 days ago
2742: SF-1 Round 5 Closed since 13 days ago
2739: LRH-1 Round 5 Closed since 20 days ago
2736: SF-1 Round 4 Closed since 27 days ago