995: 70 Residue Monomer Design: SS Design

Closed since over 11 years ago

Summary

• Created: October 08, 2014
• Expires: October 15, 2014 at 23:00 UTC
• Max points: 100

Description

In natural proteins, different amino acids show different propensities for forming secondary structures like alpha helices and beta strands. This puzzle includes a new SS Design filter that restricts the use of GLY residues in helices and sheets. There are several other filters in effect; see the puzzle comments for details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

• 1. Beta Folders 100 pts. 10,375
• 2. Contenders 84 pts. 10,370
• 3. Anthropic Dreams 70 pts. 10,305
• 4. Void Crushers 58 pts. 10,249
• 5. L'Alliance Francophone 48 pts. 10,248
• 6. Gargleblasters 39 pts. 10,221
• 7. Deleted group pts. 10,192
• 8. Go Science 26 pts. 10,185
• 9. SETI.Germany 20 pts. 10,045
• 10. HMT heritage 16 pts. 9,939

Top soloists

• 21. frood66 68 pts. 10,056
• 22. Bautho 66 pts. 10,045
• 23. Deleted player pts. 10,041
• 24. Crossed Sticks 64 pts. 9,987
• 25. O Seki To 62 pts. 9,939
• 26. Bletchley Park 61 pts. 9,929
• 27. GaryForbis 60 pts. 9,929
• 28. Sissue 59 pts. 9,915
• 29. Mike Cassidy 57 pts. 9,895
• 30. phi16 56 pts. 9,864