995: 70 Residue Monomer Design: SS Design

Closed since over 11 years ago

Summary

• Created: October 08, 2014
• Expires: October 15, 2014 at 23:00 UTC
• Max points: 100

Description

In natural proteins, different amino acids show different propensities for forming secondary structures like alpha helices and beta strands. This puzzle includes a new SS Design filter that restricts the use of GLY residues in helices and sheets. There are several other filters in effect; see the puzzle comments for details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

• 1. Beta Folders 100 pts. 10,375
• 2. Contenders 84 pts. 10,370
• 3. Anthropic Dreams 70 pts. 10,305
• 4. Void Crushers 58 pts. 10,249
• 5. L'Alliance Francophone 48 pts. 10,248
• 6. Gargleblasters 39 pts. 10,221
• 7. Deleted group pts. 10,192
• 8. Go Science 26 pts. 10,185
• 9. SETI.Germany 20 pts. 10,045
• 10. HMT heritage 16 pts. 9,939

Top soloists

• 51. BootsMcGraw 35 pts. 9,609
• 52. caglar 35 pts. 9,598
• 53. dpmattingly 34 pts. 9,596
• 54. Zuqq 33 pts. 9,596
• 55. jwk94 32 pts. 9,575
• 56. bamh 31 pts. 9,574
• 57. TheGUmmer 31 pts. 9,568
• 58. georg137 30 pts. 9,518
• 59. pvc78 29 pts. 9,515
• 60. spdenne 29 pts. 9,505