Placeholder image of a protein
Icon representing a puzzle

1125: 60 Residue Monomer Design

Closed since over 10 years ago

Intermediate Overall Design

Summary


Created
August 12, 2015
Expires
Max points
100
Description

This is a small 60 residue design puzzle. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups


  1. Avatar for Anthropic Dreams 100 pts. 10,165
  2. Avatar for Gargleblasters 2. Gargleblasters 78 pts. 10,038
  3. Avatar for Go Science 3. Go Science 60 pts. 10,029
  4. Avatar for Beta Folders 4. Beta Folders 45 pts. 10,024
  5. Avatar for Contenders 5. Contenders 33 pts. 10,011
  6. Avatar for Void Crushers 6. Void Crushers 24 pts. 10,004
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 17 pts. 9,963
  8. Avatar for Deleted group 8. Deleted group pts. 9,956
  9. Avatar for HMT heritage 9. HMT heritage 8 pts. 9,893
  10. Avatar for Italiani Al Lavoro 10. Italiani Al Lavoro 6 pts. 9,611

  1. Avatar for lim8 191. lim8 Lv 1 1 pt. 4,204
  2. Avatar for DarkArrow58 192. DarkArrow58 Lv 1 1 pt. 4,177
  3. Avatar for may of rose 193. may of rose Lv 1 1 pt. 4,176
  4. Avatar for Lolzers25 194. Lolzers25 Lv 1 1 pt. 4,152
  5. Avatar for monoleuno2015 195. monoleuno2015 Lv 1 1 pt. 4,151
  6. Avatar for aspadistra 196. aspadistra Lv 1 1 pt. 4,150
  7. Avatar for alyenation 197. alyenation Lv 1 1 pt. 4,131
  8. Avatar for maskboy 198. maskboy Lv 1 1 pt. 3,876
  9. Avatar for soadesplayer 199. soadesplayer Lv 1 1 pt. 3,493
  10. Avatar for psen 200. psen Lv 1 1 pt. 3,351

Comments


bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 25% of the residues are buried in the core of your design.

Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.