1208: 75 Residue Monomer Design: Rama Map

Closed since almost 10 years ago

Summary

• Created: March 16, 2016
• Expires: March 24, 2016 at 23:00 UTC
• Max points: 100

Description

This puzzle premieres a new tool, the Rama Map, which is meant to give players more control of the protein backbone. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

• 1. Contenders 100 pts. 10,417
• 2. Beta Folders 82 pts. 10,413
• 3. Go Science 66 pts. 10,398
• 4. Anthropic Dreams 53 pts. 10,389
• 5. Gargleblasters 42 pts. 10,371
• 6. HMT heritage 33 pts. 10,287
• 7. L'Alliance Francophone 26 pts. 10,272
• 8. Void Crushers 20 pts. 10,248
• 9. Deleted group pts. 10,181
• 10. Italiani Al Lavoro 11 pts. 9,991

Top soloists

• 1. spvincent 100 pts. 10,406
• 2. Bruno Kestemont 98 pts. 10,398
• 3. retiredmichael 96 pts. 10,391
• 4. MurloW 94 pts. 10,389
• 5. KarenCH 92 pts. 10,388
• 6. LociOiling 90 pts. 10,384
• 7. reefyrob 88 pts. 10,378
• 8. Scopper 86 pts. 10,377
• 9. Skippysk8s 84 pts. 10,371
• 10. hpaege 82 pts. 10,364

Comments

[bkoep]

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.