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1334: 90 Residue Monomer Design: Blueprint

Closed since about 9 years ago

Summary

Created: January 26, 2017
Expires: February 02, 2017 at 23:00 UTC
Max points: 100

Description

This puzzle omits the Ideal Loop Filter; we're leaving it up to players to find their own high-scoring loops! The Blueprint panel is still available, which can be accessed from the Actions menu (or the Main menu in Selection Interface). Like other recent puzzles, the Rebuild action has been disabled here; in its place we encourage players to use Remix instead. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

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14. Natural Abilities 1 pt. 4,919
15. GUGITBIOTECH 1 pt. 1,699

11. gitwut Lv 1 74 pts. 10,720
12. fiendish_ghoul Lv 1 72 pts. 10,703
13. Galaxie Lv 1 69 pts. 10,690
14. Bruno Kestemont Lv 1 67 pts. 10,686
15. dcrwheeler Lv 1 65 pts. 10,673
16. Vredeman Lv 1 63 pts. 10,639
17. caglar Lv 1 61 pts. 10,623
18. jfryk Lv 1 59 pts. 10,620
19. TomTaylor Lv 1 57 pts. 10,610
20. gmn Lv 1 55 pts. 10,604

Comments

bkoep Staff Lv 1

January 26, 2017

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Residue Count: Penalizes extra residues inserted beyond the 90 residue limit. Players may insert up to 10 extra residues.