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1355: 100 Residue Monomer Design: Helix Restrictions

Closed since about 9 years ago

Intermediate Overall Design

Summary

Created
March 18, 2017
Expires
Max points
100
Description

This puzzle is similar to recent design puzzles except that we've restricted the use of SER and THR residues in α-helices. Foldit players have submitted some stellar-looking designs recently, but we are seeing quite a lot of SER and THR residues in designed helices. Recent experiments in our lab suggest that these residues are somewhat unfavorable in helices, so in this puzzle we've restricted the use of SER and THR in helical positions. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Russian team 21. Russian team 1 pt. 4,093
  2. Avatar for Natural Abilities 22. Natural Abilities 1 pt. 3,959
  3. Avatar for Deleted group 23. Deleted group pts. 497
  4. Avatar for SciOne2017 24. SciOne2017 1 pt. 0
  5. Avatar for Window Group 25. Window Group 1 pt. 0
  1. Avatar for Tehnologik1 151. Tehnologik1 Lv 1 1 pt. 0
  2. Avatar for BIO257C-blozano 152. BIO257C-blozano Lv 1 1 pt. 0
  3. Avatar for Primalsoul 153. Primalsoul Lv 1 1 pt. 0
  4. Avatar for Flagg65a 154. Flagg65a Lv 1 1 pt. 0
  5. Avatar for bcre8tvv 155. bcre8tvv Lv 1 1 pt. 0
  6. Avatar for FarzadBekran 156. FarzadBekran Lv 1 1 pt. 0
  7. Avatar for shettler 157. shettler Lv 1 1 pt. 0
  8. Avatar for Hollinas 158. Hollinas Lv 1 1 pt. 0
  9. Avatar for Kosc hti 159. Kosc hti Lv 1 1 pt. 0
  10. Avatar for AeonFluff 160. AeonFluff Lv 1 1 pt. 0

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