Placeholder image of a protein
Icon representing a puzzle

1502: Medium Monomer Design

Closed since almost 8 years ago

Intermediate Overall Design

Summary

Created
March 27, 2018
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 75-90 residues. The starting structure has 75 residues, but more can be added at a cost of 32 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,422
  2. Avatar for Beta Folders 2. Beta Folders 65 pts. 11,346
  3. Avatar for Go Science 3. Go Science 41 pts. 11,268
  4. Avatar for Anthropic Dreams 4. Anthropic Dreams 24 pts. 11,262
  5. Avatar for Void Crushers 5. Void Crushers 14 pts. 10,954
  6. Avatar for Contenders 6. Contenders 7 pts. 10,951
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 4 pts. 10,857
  8. Avatar for Marvin's bunch 8. Marvin's bunch 2 pts. 10,654
  9. Avatar for FoldIt@Netherlands 9. FoldIt@Netherlands 1 pt. 10,269
  10. Avatar for freefolder 10. freefolder 1 pt. 9,316
  1. Avatar for actiasluna
    1. actiasluna Lv 1
    100 pts. 11,411
  2. Avatar for Enzyme 2. Enzyme Lv 1 96 pts. 11,359
  3. Avatar for LociOiling 3. LociOiling Lv 1 92 pts. 11,346
  4. Avatar for Bruno Kestemont 4. Bruno Kestemont Lv 1 88 pts. 11,268
  5. Avatar for Galaxie 5. Galaxie Lv 1 84 pts. 11,260
  6. Avatar for Deleted player 6. Deleted player pts. 11,229
  7. Avatar for johnmitch 7. johnmitch Lv 1 77 pts. 11,207
  8. Avatar for Skippysk8s 8. Skippysk8s Lv 1 74 pts. 11,204
  9. Avatar for retiredmichael 9. retiredmichael Lv 1 70 pts. 11,166
  10. Avatar for pvc78 10. pvc78 Lv 1 67 pts. 11,122

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Residue Count: Penalizes extra residues inserted beyond the starting 75, at a cost of 32 points per residue. Players may use up to 90 residues in total.