Placeholder image of a protein
Icon representing a puzzle

1769: Poly-Proline Helix Design: Round 2

Closed since over 6 years ago

Intermediate Overall Design

Summary

Created
December 04, 2019
Expires
Max points
100
Description

This is the second puzzle in our poly-proline helix design series! This is an 80 residue protein with a 12-residue long frozen poly-proline helix, and designable residues on either side. Just like in Round 1, it will be necessary to satisfy the exposed oxygens on the helix backbone to ensure that the protein stays folded! Globular structures with a hydrophobic core will have the best chance of folding in the real world.



Incorporating poly-proline helices into Foldit will help us design and make proteins with this new element! We are continuing to analyze your designs and improve the game to facilitate work with poly-proline helices.

Top groups

  1. Avatar for Hold My Beer 11. Hold My Beer 2 pts. 10,225
  2. Avatar for Team Schleswig-Holstein 12. Team Schleswig-Holstein 1 pt. 10,103
  3. Avatar for Team New Zealand 13. Team New Zealand 1 pt. 9,994
  4. Avatar for FoldIt@Netherlands 14. FoldIt@Netherlands 1 pt. 9,986
  5. Avatar for Rechenkraft.net 15. Rechenkraft.net 1 pt. 9,597
  6. Avatar for Deleted group 16. Deleted group pts. 9,177
  7. Avatar for Italiani Al Lavoro 17. Italiani Al Lavoro 1 pt. 8,851
  8. Avatar for Trinity Biology 18. Trinity Biology 1 pt. 8,797
  9. Avatar for DSN @ Home 19. DSN @ Home 1 pt. 7,542
  1. Avatar for Psych0Active 71. Psych0Active Lv 1 2 pts. 9,536
  2. Avatar for Altercomp 72. Altercomp Lv 1 2 pts. 9,528
  3. Avatar for saksoft2 73. saksoft2 Lv 1 2 pts. 9,431
  4. Avatar for fpc 74. fpc Lv 1 2 pts. 9,410
  5. Avatar for WBarme1234 75. WBarme1234 Lv 1 2 pts. 9,405
  6. Avatar for muratase 76. muratase Lv 1 2 pts. 9,334
  7. Avatar for CanWeFoldItBetter 77. CanWeFoldItBetter Lv 1 1 pt. 9,287
  8. Avatar for KotaWharton 78. KotaWharton Lv 1 1 pt. 9,211
  9. Avatar for Vincera 79. Vincera Lv 1 1 pt. 9,177
  10. Avatar for poltix 80. poltix Lv 1 1 pt. 9,177

Comments

Deleted user

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue.