Placeholder image of a protein
Icon representing a puzzle

1769: Poly-Proline Helix Design: Round 2

Closed since over 6 years ago

Intermediate Overall Design

Summary


Created
December 04, 2019
Expires
Max points
100
Description

This is the second puzzle in our poly-proline helix design series! This is an 80 residue protein with a 12-residue long frozen poly-proline helix, and designable residues on either side. Just like in Round 1, it will be necessary to satisfy the exposed oxygens on the helix backbone to ensure that the protein stays folded! Globular structures with a hydrophobic core will have the best chance of folding in the real world.



Incorporating poly-proline helices into Foldit will help us design and make proteins with this new element! We are continuing to analyze your designs and improve the game to facilitate work with poly-proline helices.

Top groups


  1. Avatar for Go Science 100 pts. 11,009
  2. Avatar for Void Crushers 2. Void Crushers 76 pts. 10,882
  3. Avatar for Gargleblasters 3. Gargleblasters 56 pts. 10,882
  4. Avatar for Beta Folders 4. Beta Folders 41 pts. 10,846
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 29 pts. 10,760
  6. Avatar for Marvin's bunch 6. Marvin's bunch 20 pts. 10,658
  7. Avatar for Contenders 7. Contenders 14 pts. 10,625
  8. Avatar for L'Alliance Francophone 8. L'Alliance Francophone 9 pts. 10,539
  9. Avatar for HMT heritage 9. HMT heritage 6 pts. 10,394
  10. Avatar for Russian team 10. Russian team 4 pts. 10,303

  1. Avatar for Psych0Active 71. Psych0Active Lv 1 2 pts. 9,536
  2. Avatar for Altercomp 72. Altercomp Lv 1 2 pts. 9,528
  3. Avatar for saksoft2 73. saksoft2 Lv 1 2 pts. 9,431
  4. Avatar for fpc 74. fpc Lv 1 2 pts. 9,410
  5. Avatar for WBarme1234 75. WBarme1234 Lv 1 2 pts. 9,405
  6. Avatar for muratase 76. muratase Lv 1 2 pts. 9,334
  7. Avatar for CanWeFoldItBetter 77. CanWeFoldItBetter Lv 1 1 pt. 9,287
  8. Avatar for KotaWharton 78. KotaWharton Lv 1 1 pt. 9,211
  9. Avatar for Vincera 79. Vincera Lv 1 1 pt. 9,177
  10. Avatar for poltix 80. poltix Lv 1 1 pt. 9,177

Comments


Deleted user

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue.