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1769: Poly-Proline Helix Design: Round 2

Closed since over 6 years ago

Intermediate Overall Design

Summary

Created
December 04, 2019
Expires
Max points
100
Description

This is the second puzzle in our poly-proline helix design series! This is an 80 residue protein with a 12-residue long frozen poly-proline helix, and designable residues on either side. Just like in Round 1, it will be necessary to satisfy the exposed oxygens on the helix backbone to ensure that the protein stays folded! Globular structures with a hydrophobic core will have the best chance of folding in the real world.



Incorporating poly-proline helices into Foldit will help us design and make proteins with this new element! We are continuing to analyze your designs and improve the game to facilitate work with poly-proline helices.

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Comments

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Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue.