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2666: Electron Density Reconstruction 137

Closed since 6 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

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  2. Avatar for SETI.Germany 12. SETI.Germany 1 pt. 63,134
  3. Avatar for Street Smarts 13. Street Smarts 1 pt. 60,517
  4. Avatar for Eὕρηκα! Heureka! 14. Eὕρηκα! Heureka! 1 pt. 60,245
  5. Avatar for BOINC@Poland 15. BOINC@Poland 1 pt. 60,004
  6. Avatar for Mahmut Oyunda 16. Mahmut Oyunda 1 pt. 54,381
  7. Avatar for People team 17. People team 1 pt. 19,398
  1. Avatar for Xendrais 21. Xendrais Lv 1 19 pts. 64,840
  2. Avatar for georg137 22. georg137 Lv 1 17 pts. 64,697
  3. Avatar for akaaka 23. akaaka Lv 1 15 pts. 64,694
  4. Avatar for TheGUmmer 24. TheGUmmer Lv 1 14 pts. 64,479
  5. Avatar for jausmh 25. jausmh Lv 1 12 pts. 64,404
  6. Avatar for NinjaGreg 26. NinjaGreg Lv 1 11 pts. 64,316
  7. Avatar for Anfinsen_slept_here 27. Anfinsen_slept_here Lv 1 10 pts. 64,279
  8. Avatar for Dr.Sillem 28. Dr.Sillem Lv 1 9 pts. 63,957
  9. Avatar for Idiotboy 29. Idiotboy Lv 1 8 pts. 63,957
  10. Avatar for zxspectrum 30. zxspectrum Lv 1 7 pts. 63,882

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.