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597: 50 Residue Symmetric Dimer Freestyle

Closed since almost 14 years ago

Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Intermediate Overall Overall Overall Overall Overall Overall Overall Overall Overall Design Design Design Design Design Design Design Design Design Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry

Summary

Created: July 10, 2012
Expires: July 23, 2012 at 07:00 UTC
Max points: 100

Description

This is a small (50 residue) symmetric dimer design puzzle. We saw some very interesting structures in the smaller 20 and 30 residue freestyles. Using 50 residues puts this in the realm of a full-scale protein domain, and docking large secondary structure motifs becomes more viable. Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together.