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656: 40 Residue Symmetric Trimer Retry

Closed since over 13 years ago

Advanced Overall Design Symmetry

Summary


Created
November 21, 2012
Expires
Max points
100
Description

This is a small (40 residue) symmetric trimer design puzzle. It is the same as 623 except the Residue Interaction Energy filter is enabled. This filter will give a score bonus or penalty based on how well your residues are scoring compared to expected values.

Remember, a symmetric protein relies not only on how well folded each part is, but also on how well they interface together - and a symmetric trimer can be thought of as having three 2-fold interfaces. Stay tuned for higher-order symmetries, like tetrahedra and octahedra!

Top groups


  1. Avatar for Team Canada 21. Team Canada 1 pt. 10,081
  2. Avatar for Mojo Risin' 22. Mojo Risin' 1 pt. 9,661
  3. Avatar for Deleted group 23. Deleted group pts. 9,500
  4. Avatar for null pointer exception 25. null pointer exception 1 pt. 8,225
  5. Avatar for DSN @ Home 27. DSN @ Home 1 pt. 0

  1. Avatar for BootsMcGraw 61. BootsMcGraw Lv 1 34 pts. 12,156
  2. Avatar for silverberg 62. silverberg Lv 1 34 pts. 12,142
  3. Avatar for Bautho 63. Bautho Lv 1 33 pts. 12,141
  4. Avatar for Mike Cassidy 64. Mike Cassidy Lv 1 32 pts. 12,140
  5. Avatar for Azukay 65. Azukay Lv 1 32 pts. 12,134
  6. Avatar for SKSbell 66. SKSbell Lv 1 31 pts. 12,131
  7. Avatar for montadar 67. montadar Lv 1 31 pts. 12,124
  8. Avatar for Deleted player 68. Deleted player pts. 12,118
  9. Avatar for Steve001 69. Steve001 Lv 1 29 pts. 12,102
  10. Avatar for steveB 70. steveB Lv 1 29 pts. 12,089

Comments


bertro Lv 1

Are you sure the Residue Interaction Energy filter is enabled? Because I see lots of Tryptophans in my solution.

tamirh Lv 1

Below your score there should be an arrow plus something that says "No bonuses, no penalties., all conditions met" (ignore the mis-punctuation) and click on the arrow.

You can click "Show" to see where (if any) of your residues are not scoring well through the Residue IE filter.

tamirh Lv 1

If you upload a screenshot I can try to explain any seemingly odd behavior (or more likely I will ask one of the scientists).

bertro Lv 1

There is nothing that shows and there are no penalties either. The message in blue says "Residue IE Score met(REQUIRED)

I have 11 Tryptophans in my solution so far.

Sorry no facility to upload a screenshot here (unlike the feedback pages).