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798: 57 Residue Monomer Design

Closed since over 12 years ago

Intermediate Intermediate Overall Overall Design Design

Summary

Created: October 19, 2013
Expires: October 28, 2013 at 23:00 UTC
Max points: 100

Description

This is a single-chain design puzzle with 57 residues. There are 3 filters enabled on this puzzle: the Residue IE Score monitors that all PHY, TYR, and TRP residues are scoring well; the Core Existence filter checks that at least 30% of the residues are buried in the core of your design; and the disulfide filter will give you a bonus for up to two disulfide bonds. The Baker Lab will run folding simulations on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 3 designs that you want us to look at, even if they are not the best-scoring solutions!